Removal of a small disk-shaped sample of tissue using a sharp, hollow device. The tissue is then examined under a microscope.
A punch is an instrument for cutting and removing a disk of tissue. A punch biopsy of the skin may for example be done to make the diagnosis of a malignancy. ... (12 Dec 1998) ... 
one in which tissue is obtained by a punch-type instrument.
Type: Term Definitions: 1. any method that removes a small cylindric specimen for biopsy by means of a special instrument that pierces the organ directly, or through the skin, or a small incision in the skin. Synonyms: trephine biopsy
Punch biopsy: A biopsy performed using a punch, an instrument for cutting and removing a disk of tissue. For example, a punch biopsy of the skin may be done to make the diagnosis of a malignancy. See also: Skin biopsy.